RIP Wuhan Virus

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California-based drugmaker Gilead Sciences announced its pricing plans for remdesivir, an antiviral COVID-19 drug candidate, saying the treatment will cost $520 per dose for U.S. private insurance companies and $390 per dose for the U.S. government.

For a majority of people who receive a five-day treatment of the drug using six vials (based on current patterns), the total for patients with private insurance in the U.S. will be $3,120. For those under U.S. government health programs the total will be $2,340 per patient.

While there is currently no FDA-approved products to treat or prevent COVID-19, remdesivir is the first antiviral medication to show effectiveness against the novel coronavirus in human clinical trials.

The pricing for the highly sought-after drugs were explained in an open letter from Daniel O'Day, the chairman and CEO of Gilead Sciences. He wrote, "There is no playbook for how to price a new medicine in a pandemic."

O'Day said the company has decided to "price remdesivir well below this value" based on tests that showed remdesivir shortened recovery time by an average of four days.

"At the level we have priced remdesivir and with government programs in place, along with additional Gilead assistance as needed, we believe all patients will have access," O'Day said.

U.S. Health and Human Services Secretary Alex Azar announced Monday that President Donald Trump secured half a million treatment courses of remdesivir for U.S. hospitals through September.

"This is the drug that, if you're hospitalized, can reduce the length of your stay by a third," Azar told ABC News chief anchor George Stephanopoulos in an interview on "Good Morning America."

The deal between the Trump administration and Gilead Sciences allows U.S. hospitals to purchase remdesivir in amounts allocated by the Department of Human and Health Services as well as state health departments.

The federal government is working with states to make sure the drug "gets to the hospitals most in need," Azar added.

Gilead originally developed remdesivir to treat patients with Ebola virus disease. In May, the Food and Drug Administration authorized the drug for emergency use to treat patients hospitalized with severe cases of COVID-19. Since then, the U.S. government has been distributing treatment courses of remdesivir that were donated by Gilead.

ABC News' Morgan Winsor contributed to this report.
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You were hacky and sneezy, but never easy.
 
Lovely how they are profitting from the pandemic like arms dealers in a war.

Gonna drop my goofball shitposting act n get human for a second.
Dexamethasone has shown more positive results but only in critically ill pts requiring supplemental oxygen. Which makes sense, steroids have always shown positive results in pts with obstructive lung issues, something the Rona causes in spades. And dexamethasone (Decadron) is cheap af. We push that like its going out of style in the ICU for post OP brain patients.

Remdesvir works (theoretically because theres still alot we don't understand about the Rona) by limiting the viruses ability to replicate within the host, I think it interferes with the RNA processes that can only happen within a host (that's why viruses need hosts, they can't reproduce on their own). By limiting the reproduction of virus, we lower the viral load in you. You'll still be sick, but hopefully not for as long. And we wont see the phenomenon that we see with this virus called the Immune storm. The immune storm happens cuz of that huge viral load (again. Theorectically) that this virus can create at a previously unforeseen rate. The immune storm is the result of the human body's immune processes going in to hyperdrive and then flying off the rails. Your body goes OH SHIT NOES flushes you full of every defense you have, opens up all your systemic systems (like how sepsis works) you get swollen and fluid over loaded quick quick but also lose your blood pressure.

Its the perfect storm, and combined with the hypercoagopathy we also see with this virus (Rona causes your body to make your blood thicker, possibly related to the immune response) is what kills ppl we are able to oxygenate (which is a feat in itself if the virus is this intense in them. Their lungs get stiff af n its like trying to pump air into bags of concrete).


We're basically throwing everything we got at this virus. Some things work better than others. Dont drink pond cleaner tho.
 
Raddy said:
Lovely how they are profitting from the pandemic like arms dealers in a war.

Gonna drop my goofball shitposting act n get human for a second.
Dexamethasone has shown more positive results but only in critically ill pts requiring supplemental oxygen. Which makes sense, steroids have always shown positive results in pts with obstructive lung issues, something the Rona causes in spades. And dexamethasone (Decadron) is cheap af. We push that like its going out of style in the ICU for post OP brain patients.

Remdesvir works (theoretically because theres still alot we don't understand about the Rona) by limiting the viruses ability to replicate within the host, I think it interferes with the RNA processes that can only happen within a host (that's why viruses need hosts, they can't reproduce on their own). By limiting the reproduction of virus, we lower the viral load in you. You'll still be sick, but hopefully not for as long. And we wont see the phenomenon that we see with this virus called the Immune storm. The immune storm happens cuz of that huge viral load (again. Theorectically) that this virus can create at a previously unforeseen rate. The immune storm is the result of the human body's immune processes going in to hyperdrive and then flying off the rails. Your body goes OH SHIT NOES flushes you full of every defense you have, opens up all your systemic systems (like how sepsis works) you get swollen and fluid over loaded quick quick but also lose your blood pressure.

Its the perfect storm, and combined with the hypercoagopathy we also see with this virus (Rona causes your body to make your blood thicker, possibly related to the immune response) is what kills ppl we are able to oxygenate (which is a feat in itself if the virus is this intense in them. Their lungs get stiff af n its like trying to pump air into bags of concrete).


We're basically throwing everything we got at this virus. Some things work better than others. Dont drink pond cleaner tho.
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The cytokine storm thing is pretty much the only thing which makes this worrisome for the young and healthy. Instead of having meds for the Gorona itself I'd rather have a steroid cocktail against this. It's likely the shitty vaccine won't even work on the possibly upcoming next wave brewing up in the Brazilian bat and human populations.
 
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